2025-07-082025-07-082024https://repositorio.ifal.edu.br/handle/123456789/1048This study aims to analyze the biological mechanisms mediated by cortisol and its implications for fetal development and maternal health, from a chemical perspective. Using a literature review methodological approach, searches were carried out in reliable databases such as Google Scholar, Pubmed and reliable websites.The results indicate that maternal stress activates the hypothalamic-pituitary-adrenal (HPA) axis, increasing the production of cortisol, which can cross the placental barrier and impact fetal neurodevelopment. Chronic exposure to cortisol is associated with structural changes in the fetal brain, risks of premature births and metabolic disorders. Interventions such as Integrative and Complementary Practices (PICs) and strengthening the social support network are highlighted as effective strategies to reduce maternal stress. It is concluded that understanding the mechanisms of stress and adopting preventive strategies are essential to promote a healthy pregnancy and better results for mothers and childrenptEstresse maternoGravidezCortisolMecanismos BiológicosAnálise Química.Trabalho de Conclusão de CursoCIENCIAS HUMANAS::SOCIOLOGIA::SOCIOLOGIA DA SAUDE